{"id":59,"date":"2024-02-20T22:45:20","date_gmt":"2024-02-20T19:45:20","guid":{"rendered":"https:\/\/artegenomics.com\/?page_id=59"},"modified":"2024-08-16T12:13:03","modified_gmt":"2024-08-16T09:13:03","slug":"artegen-e2a-pbx1-quantitative-rt-qpcr-kit","status":"publish","type":"page","link":"https:\/\/artegenomics.com\/tr\/artegen-e2a-pbx1-quantitative-rt-qpcr-kit\/","title":{"rendered":"aRTegen E2A-PBX1 Quantitative RT-qPCR Kit"},"content":{"rendered":"
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The <\/span>aRTegenTM<\/sup> E2A-PBX1 quantitative qPCR kit<\/strong> periferik kan veya kemik ili\u011fi \u00f6rneklerinde E2A-PBX1 (TCF3-PBX1 veya t(1;19) (q23;p13)) f\u00fczyon gen transkriptlerinin kantifikasyonu i\u00e7in tasarlanm\u0131\u015ft\u0131r.<\/span><\/p>

Cat No: 731803<\/em><\/p>

Temel \u00d6zellikler<\/strong><\/p>

  • E2A-PBX1 (TCF3-PBX1 veya t(1;19) (q23;p13)) f\u00fczyon gen transkriptlerini tespit eder ve kantifiye eder.<\/li>
  • FAM ve VIC\/HEX prob tabanl\u0131 deteksiyon sistemi<\/li>
  • E2A-PBX1 ve ABL transkriptlerinin 10 kopyadan daha az\u0131n\u0131 tespit edebilme kapasitesine sahiptir.<\/li>
  • Ters transkripsiyon ve qPCR ad\u0131mlar\u0131n\u0131n ayr\u0131 ayr\u0131 optimize edilmesi ve ileri kullan\u0131m i\u00e7in cDNA stokunun olu\u015fturulabilmesi.<\/li>
  • \u0130ki a\u015famal\u0131 qPCR reaksiyonu, testin y\u00fcksek duyarl\u0131l\u0131\u011fa sahip olmas\u0131n\u0131 ve s\u0131n\u0131rl\u0131 miktardaki numunelerle dahi etkili \u015fekilde \u00e7al\u0131\u015fmas\u0131n\u0131 sa\u011flar.<\/li><\/ul>

    Akut lenfoblastik l\u00f6semi (ALL), %3 ila %5 oran\u0131nda g\u00f6r\u00fclen, kemik ili\u011finde, periferik kanda ve di\u011fer organlarda olgunla\u015fmam\u0131\u015f lenfoid h\u00fccrelerin proliferasyonu ile karakterize hematolojik bir neoplazidir. Tekrarlayan kromozomal translokasyon t(1;19), ALL\u2019ye \u00f6zg\u00fc iyi bilinen bir sitogenetik de\u011fi\u015fiklik olup, 19p13 b\u00f6lgesindeki transkripsiyon fakt\u00f6r\u00fc 3 geninin (TCF3, \u00f6nceki ad\u0131yla E2A) 1q23 b\u00f6lgesindeki pre-B h\u00fccre l\u00f6semi homeobox 1 geni (PBX1) ile f\u00fczyona u\u011framas\u0131na ve TCF3-PBX1 transkriptlerinin olu\u015fmas\u0131na neden olur. Bu test, transkript d\u00fczeylerinin izlenmesi amac\u0131yla TCF3-PBX1 f\u00fczyon transkriptlerinin tespiti ve kantifikasyonu i\u00e7in kullan\u0131labilir.<\/p>

    The aRTegenTM<\/sup> E2A-PBX1 quantitative qPCR kit<\/strong>\u00a0yaln\u0131zca ara\u015ft\u0131rma ama\u00e7l\u0131d\u0131r; tan\u0131sal kullan\u0131m i\u00e7in uygun de\u011fildir.<\/em><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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    \n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\"aRTegenTM\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"

    The aRTegenTM E2A-PBX1 quantitative qPCR kit is intended for quantitation of E2A-PBX1 (TCF3-PBX1 or t(1;19) (q23;p13))\u00a0 fusion gene transcripts in peripheral blood or bone marrow samples. Cat No: 731803 Key Features Detect and quantify E2A-PBX1 (TCF3-PBX1 or t(1;19) (q23;p13)) fusion gene transcripts. FAM and VIC\/HEX probe-based detection system Capable of detecting less than 10 copies […]<\/p>","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"class_list":["post-59","page","type-page","status-publish","hentry"],"blocksy_meta":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/artegenomics.com\/tr\/wp-json\/wp\/v2\/pages\/59","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/artegenomics.com\/tr\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/artegenomics.com\/tr\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/artegenomics.com\/tr\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/artegenomics.com\/tr\/wp-json\/wp\/v2\/comments?post=59"}],"version-history":[{"count":43,"href":"https:\/\/artegenomics.com\/tr\/wp-json\/wp\/v2\/pages\/59\/revisions"}],"predecessor-version":[{"id":533,"href":"https:\/\/artegenomics.com\/tr\/wp-json\/wp\/v2\/pages\/59\/revisions\/533"}],"wp:attachment":[{"href":"https:\/\/artegenomics.com\/tr\/wp-json\/wp\/v2\/media?parent=59"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}