{"id":61,"date":"2024-02-20T22:46:46","date_gmt":"2024-02-20T19:46:46","guid":{"rendered":"https:\/\/artegenomics.com\/?page_id=61"},"modified":"2024-08-16T12:14:49","modified_gmt":"2024-08-16T09:14:49","slug":"artegen-mll-af4-quantitative-rt-qpcr-kit","status":"publish","type":"page","link":"https:\/\/artegenomics.com\/tr\/artegen-mll-af4-quantitative-rt-qpcr-kit\/","title":{"rendered":"aRTegen MLL-AF4 Quantitative RT-qPCR Kit"},"content":{"rendered":"
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The <\/span>aRTegenTM<\/sup> MLL-AF4 quantitative qPCR kit<\/strong> periferik kan veya kemik ili\u011fi \u00f6rneklerinde MLL-AF4 (t(4;11) (q21;q23)) f\u00fczyon gen transkriptlerinin kantifikasyonu i\u00e7in tasarlanm\u0131\u015ft\u0131r.<\/span>
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Cat No: 556875<\/em><\/p>\n

Temel \u00d6zellikler<\/strong><\/p>\n

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  • MLL-AF4 (t(4;11) (q21;q23)) f\u00fczyon gen transkriptlerini tespit eder ve kantifiye eder.<\/li>\n
  • FAM ve VIC\/HEX prob tabanl\u0131 deteksiyon sistemi<\/li>\n
  • MLL-AF4 ve ABL transkriptlerinin 100 kopyadan daha az\u0131n\u0131 tespit edebilme kapasitesine sahiptir.<\/li>\n
  • Ters transkripsiyon ve qPCR ad\u0131mlar\u0131n\u0131n ayr\u0131 ayr\u0131 optimize edilmesi ve ileri kullan\u0131m i\u00e7in cDNA stokunun olu\u015fturulabilmesi.<\/li>\n
  • \u0130ki a\u015famal\u0131 qPCR reaksiyonu, testin y\u00fcksek duyarl\u0131l\u0131\u011fa sahip olmas\u0131n\u0131 ve s\u0131n\u0131rl\u0131 miktardaki numunelerle dahi etkin \u015fekilde \u00e7al\u0131\u015fmas\u0131n\u0131 sa\u011flar.<\/li>\n<\/ul>\n

    Mixed Lineage Leukemia (MLL<\/em>gen d\u00fczenlenmeleri, insan l\u00f6semileri aras\u0131nda en s\u0131k g\u00f6r\u00fclen genetik de\u011fi\u015fiklikler aras\u0131ndad\u0131r. Bunlar aras\u0131nda MLL\u2013AF4 akut lenfoblastik l\u00f6semi (ALL), MLL ve AF4 genleri aras\u0131nda ger\u00e7ekle\u015fen dengeli bir translokasyonun [t(4;11)(q21;q23)] sonucunda ortaya \u00e7\u0131kar ve infant, \u00e7ocuk ve yeti\u015fkin ALL vakalar\u0131nda yakla\u015f\u0131k %5\u20136 oran\u0131nda g\u00f6r\u00fcl\u00fcr. Bu alt tip, genellikle k\u00f6t\u00fc prognoz ile ili\u015fkilidir. Pediatrik ALL olgular\u0131nda MLL-AF4 f\u00fczyon transkriptlerinin tespiti ve kantifikasyonu, prognozun belirlenmesi ve uygun tedavi yakla\u015f\u0131mlar\u0131n\u0131n planlanmas\u0131 a\u00e7\u0131s\u0131ndan kritik \u00f6neme sahiptir. aRTegenTM<\/sup> MLL-AF4 quantitative qPCR kit<\/strong> transkript d\u00fczeylerinin izlenmesi amac\u0131yla MLL-AF4 f\u00fczyon transkriptlerinin tespiti ve kantifikasyonu i\u00e7in kullan\u0131labilir.<\/p>\n

    The aRTegenTM<\/sup> MLL-AF4 quantitative qPCR kit<\/strong> yaln\u0131zca ara\u015ft\u0131rma ama\u00e7l\u0131d\u0131r; tan\u0131sal kullan\u0131m i\u00e7in uygun de\u011fildir.<\/em><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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    \n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\"The\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"

    The aRTegenTM MLL-AF4 quantitative qPCR kit is intended for quantitation of MLL-AF4 (t(4;11) (q21;q23))  fusion gene transcripts in peripheral blood or bone marrow samples. Cat No: 556875 Key Features Detect and quantify MLL-AF4 (t(4;11) (q21;q23)) fusion gene transcripts. FAM and VIC\/HEX probe-based detection system Capable of detecting less than 100 copies of MLL-AF4 and ABL […]<\/p>","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"class_list":["post-61","page","type-page","status-publish","hentry"],"blocksy_meta":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/artegenomics.com\/tr\/wp-json\/wp\/v2\/pages\/61","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/artegenomics.com\/tr\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/artegenomics.com\/tr\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/artegenomics.com\/tr\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/artegenomics.com\/tr\/wp-json\/wp\/v2\/comments?post=61"}],"version-history":[{"count":22,"href":"https:\/\/artegenomics.com\/tr\/wp-json\/wp\/v2\/pages\/61\/revisions"}],"predecessor-version":[{"id":537,"href":"https:\/\/artegenomics.com\/tr\/wp-json\/wp\/v2\/pages\/61\/revisions\/537"}],"wp:attachment":[{"href":"https:\/\/artegenomics.com\/tr\/wp-json\/wp\/v2\/media?parent=61"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}